Recognition of microbial glycans by soluble human lectins
نویسندگان
چکیده
منابع مشابه
Recognition of Microbial Glycans by Human Intelectin
The glycans displayed on mammalian cells can differ markedly from those on microbes. Such differences could, in principle, be read by carbohydrate-binding proteins, or lectins. We used glycan microarrays to show that human intelectin-1 (hIntL-1) does not bind known human glycan epitopes but interacts with multiple glycan epitopes found exclusively on microbes: β-linked Dgalactofuranose (β-Galf)...
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1Department of Applied Biochemistry, Tokai University, Hiratsuka 259-1292, Japan 2Scottish National Blood Transfusion Service, National Science Laboratory, Edinburgh EH177QT, UK 3National Research Laboratory of Defense Proteins, Global Research Laboratory of Insect Symbiosis, College of Pharmacy, Pusan National University, Busan 609735, Republic of Korea 4Department of Microbiology and Immunolo...
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Lectins extracted from corn (Zea mays L.) kernel with Tris-HCl buffer pH 7.5 were isolated from the crude extract by affinity chromatography on Sepharose 6B-N-acetyl-d-galactosamine and Sepharose 6B-methylalpha-d-mannoside, and also by lectin affinity chromatography using concanavalin A and Lens culinaris lectin as ligands. According to preferential monosaccharide specificity, salt-soluble lect...
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ژورنال
عنوان ژورنال: Current Opinion in Structural Biology
سال: 2017
ISSN: 0959-440X
DOI: 10.1016/j.sbi.2017.04.002